Physical Activity & Exercise
Biomarkers & Diagnostics
Supplements & Pharmaceuticals

Peter Attia Longevity Protocol

1. Author Information

Dr. Peter Attia is a physician, researcher, and expert in the fields of longevity and performance optimization. Known for his evidence-based and pragmatic approach to extending healthspan, he founded Attia Medical, PC, a practice dedicated to the science of longevity. Dr. Attia has contributed to longevity science through his popular podcast, “The Peter Attia Drive,” and his book, Outlive: The Science and Art of Longevity, which provides a deep dive into practical strategies for living a longer, healthier life.


2. Protocol Objective

Main Goal: To extend healthspan by reducing the risks of major diseases like cardiovascular disease, cancer, neurodegenerative diseases, and type 2 diabetes, which Dr. Attia calls the "Four Horsemen of Death." The protocol is designed for individuals who aim to improve their longevity and physical performance, particularly mid-life individuals who seek preventive approaches to maintain a high quality of life in later years.


3. Core Principles

  • Preventive Medicine: Emphasis on early intervention and management of risk factors for chronic diseases.
  • Data-Driven Personalization: Recommends regular health monitoring, such as bloodwork and imaging, to inform personalized health interventions.
  • Zone 2 Cardio and VO₂ Max Optimization: Advocates for aerobic conditioning and strength training to maintain cardiovascular health and physical function with age.
  • Hormesis: Uses controlled physical stressors, like intermittent fasting and cold exposure, to enhance resilience.
  • Nutrition and Blood Sugar Control: Focuses on managing blood glucose and insulin levels to reduce risks of metabolic syndrome and type 2 diabetes.

4. Nutrition Recommendations

  • Low Glycemic Diet: Recommends a low-carb diet or ketogenic approach to stabilize blood sugar levels and reduce inflammation.
  • Time-Restricted Feeding (TRF): Suggests limiting the eating window, often within 8-10 hours, to support metabolic flexibility.
  • Protein Intake: Prioritizes adequate protein intake to maintain muscle mass, particularly from animal sources for optimal amino acid profile.
  • Omega-3 Fatty Acids: Emphasizes the importance of omega-3s (like EPA and DHA) from fish or supplements to support cardiovascular health.

5. Supplements and Vitamins

  • Omega-3 Supplements: Recommends fish oil to maintain a healthy Omega-6 to Omega-3 ratio.
  • Magnesium: Advocates for magnesium supplements to support cardiovascular and muscle function.
  • Vitamin D: Suggests vitamin D supplements for immune and bone health, tailored to individual levels.
  • Electrolytes: Recommends electrolytes for individuals on a low-carb diet to maintain hydration and muscle function.

6. Physical Activity

  • Zone 2 Cardio: Dr. Attia emphasizes aerobic training at “Zone 2” intensity (sub-threshold cardio) to improve mitochondrial function and endurance. Aims for at least 3-4 sessions per week, lasting 45-60 minutes each.
  • Strength Training: Focus on compound lifts (squats, deadlifts) and functional movements to maintain muscle mass and bone density. Recommended frequency is 2-3 times per week.
  • VO₂ Max Intervals: Incorporates high-intensity interval training (HIIT) to boost cardiovascular capacity and metabolic health.

7. Sample Routine of the Author

Dr. Attia typically begins his day with a morning workout, incorporating strength or aerobic training. He follows a time-restricted eating pattern, consuming nutrient-dense meals with an emphasis on protein and healthy fats. Supplements like omega-3 and vitamin D are taken alongside meals. He monitors his progress with regular lab tests and imaging.


8. Mental and Cognitive Exercises

  • Meditation and Mindfulness: Recommends daily meditation for stress reduction and cognitive resilience.
  • Sleep Optimization: Prioritizes sleep hygiene to ensure restorative rest, emphasizing a consistent sleep schedule and limiting blue light exposure before bed.

9. Additional Procedures

  • Cold Exposure: Suggests cold showers or ice baths for a hormetic stressor that may support fat loss and boost metabolism.
  • Fasting Protocols: Practices extended fasts (24-72 hours) periodically to promote autophagy and metabolic health.

10. Scientific Basis

Dr. Attia’s protocol is grounded in research from fields such as cardiovascular health, metabolic syndrome, and aging biology. Studies indicate that Zone 2 training, caloric restriction, and nutrient-dense diets can reduce risk factors for the major causes of mortality, while strength training is shown to support mobility and reduce fall risk in older adults.


11. Side Effects and Risks

Potential Risks: Prolonged fasting and cold exposure may not suit individuals with certain medical conditions (e.g., low blood pressure or metabolic issues). It’s essential to consult with a healthcare provider before starting fasting protocols or intense physical routines to avoid adverse effects.


12. Personalization

This protocol is most effective for individuals focused on preventive health, physical performance, and reducing the risk of chronic diseases. Dr. Attia tailors his advice to individual health metrics, encouraging users to personalize their approach based on their specific risk factors and health goals.


Websites:

x.com/PeterAttiaMD
peterattiamd.com


Key Phrases:

Longevity, Physical Performance, Preventive Health, Nutrition, Zone 2 Cardio, Strength Training, Fasting, Metabolic Flexibility, Cardiovascular Health

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